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The plasmacyt-oid cells in this patient are relatively small and well differentiated . They closely resemble normal plasma cells. Chromatin is clumped, and often of the “clockface” type. Nucleoli are inconspicuous if visible. Binucleate forms are noted near 12 and at 3 o’clock.
Occasional binucleate myeloma cells are present – there are two in this field. This finding does not offer any diagnostic or prognostic information. In general, binucleate forms may be present in any type of myeloma. Can you find 3 neutrophils, 1 metamyelocyte and 2 myelocytes in this field? Mature myeloma cells with ‘clock-face’ chromatin are sometimes referred to as Marschelko cells.